Comparison of drug dependence formation in naive and drug dependence-experienced rats
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چکیده
منابع مشابه
Commentary: New View on Treatment of Drug Dependence
In the 1960s, discovery of pleasure system (defined as reward system) in the brain that may underlie drug reward and addiction encouraged many scientists to investigate the mechanisms by which drug abuse affects central nervous system function. In this regard, investigators developed several drugs targeting the brain reward system for drug dependence therapy. However, no positive results obtain...
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Subjects, methods, and results In 1988-9 we interviewed a random sample of 1751 men serving a prison sentence (5% of the population) about drug use in the six months before arrest. Dependence on a drug was defined as in the previous study. Drug users were asked about previous contact with treatment agencies and their current attitude towards treatment. A question about drug use within prison wa...
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Drug-dependence disorders (we focus here on cocaine, opioid, and nicotine dependence) are genetically influenced. Risk genes have been located based primarily on genetic linkage studies, and identified primarily based on genetic association studies. In this article we review salient results from linkage, association, and genome-wide association study methodologies, and discuss future prospects ...
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ژورنال
عنوان ژورنال: Folia Pharmacologica Japonica
سال: 1975
ISSN: 0015-5691,1347-8397
DOI: 10.1254/fpj.71.157